17 April 2014

Two P4L devices were honored with the Innovation Award

The Bio Particle Explorer and the Optical Neuro-Monitor, two successful examples of interdisciplinary cooperation in the field of biophotonics, were 1st and 2nd runner up for the Innovation Village Award at Photonics Europe 2014 in Brussels. Both devices were developed within Photonics4Life, the European Network of Excellence for Biophotonics, and within the research focus Biophotonics which is funded by the Federal Ministry of Education and Research.

The jury recognized the level of innovation, the value of the product for society, the business opportunity as well as on what level the product provides a solution to customer needs. Dr. Stephan Stöckel, University Jena, representing the BioParticle Explorer and Dr. Udo Weigel, HemoPhotonics, representing the Optical Neuro-Monitor, received a certificate as well as a monetary prize amounting 500 euros.

The technology of the Bio Particle Explorer was developed by the Leibniz Institute of Photonic Technology and the University Jena. The medium-sized enterprise rap.ID from Berlin transferred the technology into the product Bio Particle Explorer and developed it further to market maturity.

The rapid on-site monitor can accurately characterize for exeample a single bacterium within a second and allows for the first time a real-time monitoring of germs such as bacteria, funguses, and yeasts from air or liquids. It enables operators of cleanrooms to immediately and specifically respond to possible contamination and to prevent loss of production e.g. in drug manufacture. Other applications such as hygienic monitoring of food or in hospitals are currently explored. In some situations the mere presence of a single bacterial cells is fatal, for example, in the air of operating rooms or in food processing. There it is crucial to identify them quickly and precisely to ward off impending damage immediately. The classical can not keep up: it requires a lengthy cultivation, which sometimes can last several days. Genetic testing (DNA assays) require less time, but can only search for certain previously determined bacteria.

The Diffuse Optical Neuro-Monitor was developed by the Institute for Photonic Sciences, ICFO, and the company Hemospec. The portable device provides diagnostic information about the local, micro-vascular cerebral perfusion based on diffuse correlation spectroscopy (DCS). DCS measures the motion of the red blood cells as the primary scatterers in the tissue volume under investigation. This motion results in a decay of the intensity auto-correlation of the detected light from a coherent light source. DCS was extensively validated against a multitude of modalities in pre-clinical studies and in clinics.

Ischemic stroke is the leading cause of morbidity and long term disability worldwide. The local micro-vascular cerebral blood flow (CBF) plays a crucial role. Its disruption is either the cause of the problem, e.g. the blockage of a major artery as in ischemic stroke, or the main aim of the management, .e. g. restoration of sufficient blood flow to ischemic areas.

Round Robin Experiment

Raman spectroscopy has already proved its effectiveness in many cases for medical diagnostics such as for cancer, cardiovascular diseases and infections. However, there are no standards in the different working groups, e.g. for sample preparation, implementation of the Raman experiments, spectra pre-treatment, data evaluation, etc.In a round robin experiment, the required groundwork will take place in order to define standardised Raman measurement methods, which will be fundamental for establishing Raman spectroscopy for clinical diagnostic procedures.

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